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Endogenous collagen synthesis requires two types of signals. Signalling peptides (Matrixyl) tell fibroblasts that there's damaged collagen — and activate them to produce more. Vitamin C is the enzymatic cofactor that stabilises newly synthesised collagen. Without vitamin C, the collagen produced by peptides is structurally weak. The combination isn't marketing — it's biochemistry.
Complete Mechanism: Why Both Together Outperform Each Alone
Peptides (Matrixyl, GHK-Cu): bind to receptors in dermal fibroblasts and activate transcription of collagen type I, III and IV genes. Result: more collagen synthesised.
Vitamin C (cofactor of prolyl hydroxylase and lysyl hydroxylase): stabilises the collagen triple helix by adding hydroxyl bridges. Without vitamin C, synthesised collagen collapses. Result: stronger and more durable collagen.
Vitamin C deficit in the dermis — even subclinical — reduces peptide efficacy. The combination ensures that the synthesis signal (peptides) finds the structural conditions to produce functional collagen (vitamin C).
The Collagen Booster Serum combines both actives in a night formula — when skin has greater permeability and collagen synthesis is at its peak.
Collagen Booster Serum →When Results Are Visible
- 4–6 weeks: skin appears firmer, fine lines less pronounced
- 8–12 weeks: measurable wrinkle reduction in peptide studies (Matrixyl)
- 3–6 months: changes in skin density and elasticity
The Complete Collagen Protocol
Morning: Peptide + HA Anti-Ageing Serum → Vitamin C → SPF
Night: Collagen Booster Serum → Bakuchiol (alternating nights) → Ceramide Cream
To maximise: the Peptide Anti-Ageing Serum in the morning amplifies the Collagen Booster's work at night. The two serums cover the full 24-hour synthesis cycle.
Anti-Ageing Serum with Peptides →